Abstract

MARCH VILLALBA, J.A. et al. Radical cystectomy as a muscle-invasive bladder cancer treatment in elderly patients. Actas Urol Esp [online]. 2008, vol.32, n.7, pp.696-704. ISSN 0210-4806.

Introduction: Radical cystectomy in elderly is a controversial issue that increases importance overtime because average life span is growing. Objetive: The porpouse of our work was to analize the differences about perioperative and later outcomes between ages of patients with muscle-invasive bladder neoplasm treated with radical cystectomy. Material and methods: We retrospectively reviewed the records of patients who underwent radical cystectomy for muscle-invasive bladder cancer. Two age groups were compared: <70 years old at time of cystectomy (n=55) and =70 years (n=57). Results: There was no difference between both age groups about: time of surgery, intraoperative complications (<70=21,8%,=70=31,6%), postoperative mortality (<70=3,6%, =70=8,8%), minor (<70=18,2%, =70=26,3%) and major medical postoperative complications (<70=7,3%, =70=8,8%), late outcomes as cancer-specific morby-mortality and actuarial overall survival stratified by patient age. The rate of major postoperative complications (<70=23,6%, =70=43,9%) as well as the mean length of hospital stay (<70=10,2, =70=15,2 days) differed significantly between the two age groups. Age and cardiovascular risk factors were independient predictive factors of mayor postoperative complications. Conclusions: Radical cystectomy could be performed in carefully selected elderly patients.

Keywords : Elderly; Cystectomy; Bladder neoplasm.

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