Abstract

PENA-GARIJO, Josep  and  MONFORT-ESCRIG, Cristina. Cognition in schizophrenia. State of the art (I): assessment methods and neural correlates. Rev. Asoc. Esp. Neuropsiq. [online]. 2020, vol.40, n.137, pp.109-130.  Epub Dec 28, 2020. ISSN 2340-2733.  https://dx.doi.org/10.4321/s0211-57352020000100007.

Research suggests that symptoms, neurocognition and social cognition influence each other and are related to psychosocial functioning in schizophrenia. The measurement of neurocognitive deficits in schizophrenia has been remarkably developed with the "MATRICS" protocol. In addition, these impairments have been linked to abnormal functioning of the dorsolateral prefrontal cortex and problems in its connectivity with other brain areas. On the other hand, deficits in social cognition have been linked to the so-called "social brain" and have been related to symptoms and psychosocial functioning. Attention, memory and executive function seem to be altered in schizophrenia, relating to abnormal functioning of brain structures and their connectivity between them. Impairments in different social cognitive domains, linked to the so-called "social brain", could be an endophenotypic marker of schizophrenia. However, possible methodological and conceptual issues prevent to take these conclusions as definitive.

Keywords : schizophrenia; social cognition; neurocognition; social brain; social functioning.

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