Abstract

GONZALEZ SARMIENTO, E. et al. Modification of the metabolic parameters and microalbuminuria in patients with diabetes mellitus type 2 treated with acarbose. An. Med. Interna (Madrid) [online]. 2001, vol.18, n.5, pp.10-12. ISSN 0212-7199.

Objective: to determinate the influence of the acarbosa and microalbuminuria on metabolic parameters in patients diabetics type 2. Research desing and methods: We are studied 92 patients with diabetes type 2, treated with Acarbose alone or with insuline or oral antidiabetics We are determinated the values of HbA1c, total cholesterol, HDL, LDL, triglycerides and microalbuminuria, before and after or the treatment with acarbose. Results: The patients presented globally a statistically significant improvement in the levels of Hb A1 c, triglycerides and microalbuminuria. In the group treatise with 300 mg/day of acarbose it was observed a significant decrease of the values of Hb A1c and triglycerides independently of the associated treatment. In the group treated with 150 mg/day the improvement only it was statistically significant for the levels of Hb A1c. Conclusions: The treatment with acarbose produces an improvement in the levels of Hb A1c independently of the administered dose and of the triglycerides in patients treated wth 300 mg/day without relation to associated treatments Therefore, he acarbose win be considered an effective medication to improve the metabolic contral to prevent the cardiovascular risk in those patients

Keywords : Acarbose; Lipids; Microalbuminuria.

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