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Anales de Medicina Interna
Print version ISSN 0212-7199
Abstract
GONZALEZ BARCALA, F. J.; ZAMARRON SANZ, C.; SALGUEIRO RODRIGUEZ, M. and RODRIGUEZ SUAREZ, J. R.. Non-invasive ventilation in chronic obstructive pulmonary disease patients with acute respiratory hypercapnic failure in a conventional hospital ward. An. Med. Interna (Madrid) [online]. 2004, vol.21, n.8, pp.13-19. ISSN 0212-7199.
Objective: To analyze chronic obstructive lung disease (COPD) subjects in acute hypercapnic failure who were treated with non-invasive mechanical ventilation in a general respiratory ward. Methods: This was a two-year prospective study of 35 patients with acute exacerbation of COPD and mean FEV1/FVC relation in stable condition of 55.3 ± 14.8% of predicted that were treated with positive pressure respiration using a facemask in a general respiratory ward. 17 (48,5%) receive long-term oxygen therapy. Analysis was made of blood gases, before and after treatment of non-invasive ventilation, complications, and failure during treatment. Results: A significant improvement in blood gases was observed 24 hours after non-invasive ventilation treatment. The mean hospital stay was of 15.0 ± 9.1 days and failures were registered in 3 cases (8.5%). Facial scares were the most common complication (13 patients) but it was possible to continue treatment. Conclusions: Non-invasive ventilation is a viable treatment for patients with chronic obstructive lung disease and acute hypercapnic failure being treated in a general respiratory ward.
Keywords : Mechanical Ventilation; Positive Pressure Respiration; Chronic Obstructive Airway Disease; Respiratory Insufficiency; Acidosis respiratory.