Abstract

KHOSRAVI SHAHI, P.  and  CASTILLO RUEDA, A. del. Histiocytic sarcoma: a case report and review of the literature. An. Med. Interna (Madrid) [online]. 2005, vol.22, n.4, pp.35-37. ISSN 0212-7199.

Histiocytic sarcoma is a rare neoplasm, and its aetiology is unknown. It is a malignant proliferation of neoplastic cells showing immunophenotypic and morphologic features similar to tissue histiocytes. The clinical course of histiocytic sarcoma is usually agressive. The signs and symptoms of histiocytic sarcoma are systemic symptoms (fever, weight loss), hepatosplenomegaly, adenopathies, intestinal obstruction, rash and pancytopenia. We present the case of a 75 years old woman, with fever, wieght loss, anorexia, fatigue, splenomegaly and pancytopenia. Bone marrow examination showed the diagnosis of histiocytic sarcoma.

Keywords : Histiocytic sarcoma; Pancytopenia; Lysozyme; True histiocytic lymphoma; CD68.

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