Abstract

GARCIA GARCIA, V; GONZALEZ-MOLES, MA  and  BASCONES MARTINEZ, A. Blc-2, ki-67 and caspasa-3 expression in oral cancer lesions: Preliminary results. Av Odontoestomatol [online]. 2006, vol.22, n.5, pp.263-269. ISSN 2340-3152.

Oral cancer represents 2%-4% of all types of cancer that are diagnosed and epidermal carcinoma is the most common tumour found in oral cavity. Some experimental studies have shown that TNM classification is not useful when you want to know tumour prognosis. Now we are in the modern inmunohistochemical period with new techniques for cancer diagnose. Material and method: use the peroxidase-antiperoxidase inmunohistochemical technique to detect bcl-2, caspasa-3 and Ki-67 molecules in cancerous lesions. Preliminary results and discussion: molecular detection of the antiapoptotic bcl-2 molecule, the proapoptotic caspasa-3 molecule and the cellular proliferation indicator Ki-67 will show us about the gravity of the patient situation.

Keywords : Epidermal carcinoma; Inmunohistochemistry.

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