Abstract

DE CASTRO AVELLANER, M.E.; FIGUEIREDO, R.; BERINI AYTES, L.  and  GAY ESCODA, C.. Cystoadenoma of minor salivary glands: Two case reports and review of the literature. Av Odontoestomatol [online]. 2011, vol.27, n.3, pp.129-136. ISSN 2340-3152.

Introduction: Cystoadenomas are considered uncommon neoplasms of epithelial salivary origin and are characterized by having multiple papillary projections and microcystic spaces recovered by cuboid and cilindric cells. Cystoadenoma is defined by the WHO as a salivary neoplasia very similar to Warthin´s tumour, but lacking lymphoid cells. The most common sites are the larynx, nasopharynx and lachrymal gland, although in some occasions these lesions can be found in the lips, buccal mucosa, palate and tonsillae. Thus 35% of cystoadenomas have minor salivary gland locations. Case reports: Histological samples revealed 2 cases of minor salivary glands cystoadenomas in patients who attended the Oral Surgery department of the University of Barcelona. A man aged 79 years old with medical history of non insulin-dependent diabetes and gastric ulcer and another male patient with 86 years old with a previous history of depression. Macroscopic examination showed a well-limited tumour of tender consistency, mobile and without ulcerous surface. In the first case, the tumour was located in the lower lip, it measured 1 cm of length and 0.7 cm of width, had the same colour as the adjacent mucosa and was slightly painful when pressured. In the second case, the tumour was over the right retromolar area, and presented no symptoms and had a blue colour. The lesion measured 1.7 cm of length and 1 cm of width. The patients referred that the lesions were present for 2 to 3 months approximately. Surgical removal with margins was performed in both cases and the samples were sent for histological analysis. Discussion: Cystoadenomas are uncommon salivary benign neoplasms described for the first time by Skorpil in 1941, and there has been some controversy about its origin and definition. WHO classification of salivary tumours in 1972 included this lesion as an adenoma. However in the latest review made in 2005, the cystoadenoma is considered a separate histological entity. We found two patients with these lesions diagnosed between 1997 and 2006. According to the literature, the frequency of cystoadenomas varies between 2% and 4.7% of all the minor salivary gland tumours. No etiopatogenic factors have been described and some authors consider this to be a real neoplasia, while others believe it is a ductal epithelium hyperplasia. Cystoadenomas are usually diagnosed between the 6th and the 8th decades of life. The treatment of choice is the local excision. No recurrences have been reported unless the lesion isn't fully removed.

Keywords : Cystoadenoma; adenoma; minor salivary glands.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )