Abstract

AMIGO VASQUEZ, S; QUINTANILLA SFEIR, M  and  HIDALGO RIVAS, A. Aggressive central giant cell granuloma: report of an atypical case. Av Odontoestomatol [online]. 2021, vol.37, n.4, pp.183-185.  Epub Dec 05, 2022. ISSN 2340-3152.  https://dx.doi.org/10.4321/s0213-12852021000400006.

Central giant cell granuloma (CGCG) is an infrequent benign, localized, potentially aggressive, non-odontogenic osteolytic lesion, characterized by the presence of giant cells in a vascular stroma. CGCG is seen mainly in women, more frequently in the first two decades of life. Radiographically, CGCG can be seen from a cystic-like radiolucent image, to an extensive multilocular image, with less defined margins. According to clinical, radiographic and histological aspects of CGCG, an aggressive type has been proposed, which is characterized by rapid growing, pain, paresthesia, expansion/perforation of cortical bone, rizalisis, and high rates of recurrence. Of controversial etiology, CGCG has been described as a reparative lesion, associated to trauma. However, potentially destructive, expansive and infiltrative characteristics have been observed in CGCG. An atypical case of an aggressive CGCG is presented.

Keywords : Central giant cell granuloma; CGCG; mandible; aggressive; case report.

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