Abstract

RECHE-SAINZ, J.A.; PERAL-ORTIZ DE LA TORRE, M.J.; CARPIO-BAILEN, R.  and  TOLEDANO-FERNANDEZ, N.. Diffuse large B cell lymphoma presenting with a bilateral serous macular detachment. Arch Soc Esp Oftalmol [online]. 2007, vol.82, n.9, pp.559-562. ISSN 0365-6691.

Clinical case: A 42 year-old male was assessed for a subacute, bilateral and progressive visual loss. His medical history included chronic hepatitis C infection and Evans syndrome. On fundal examination, multiple areas of neurosensorial and retinal pigmented epithelium detachment were observed in the region of both macula. A few days later, his general health deteriorated and he was noted to have a high fever and adenopathy. Biopsy of an enlarged lateral cervical lymph node demonstrated the existence of a diffuse large B cell lymphoma. After several cycles of chemotherapy, he experienced a progressive and bilateral improvement of his vision, which was accompanied by a reattachment of the previously detached areas. Discussion: A bilateral and serous macular detachment may be the initial manifestation of a diffuse large B cell lymphoma. The prognosis of these retinal lesions may be favourable if lymphoma remission is achieved.

Keywords : Retina; macula; serous detachment; lymphoma; diffuse large B cell lymphoma.

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