Abstract

WIWANITKIT, V.. Potential protein post-translational modifications and find potential single amino acid substitutions in hepatitis B large envelope protein. Rev. esp. enferm. dig. [online]. 2008, vol.100, n.3, pp.153-155. ISSN 1130-0108.

Post-translational modifications of proteins control many biological processes. This is also important process in virus including hepatitis B. However, there is no in-depth study on the whole hepatitis B virus large envelope protein. In this work, potential protein post-translational modifications in hepatitis B virus large envelope protein were determined by a standard bioinformatics technique. Furthermore, potential single amino acid substitutions in hepatitis B large envelope protein were also determined. It can be seen that there are possible 3 potential protein were post-translational modifications with 1 possible single substitution. This data can be useful for further study on hepatitis B virus mutant as well as planning for new vaccine production.

Keywords : Post-translational modifications; Hepatitis B; Envelope; Single substitution.

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