Abstract

GALVEZ, R. et al. Neurophatic pain as a cause of anxiety, depressión and sleep disturbance in standard condition of care: DONEGA naturalistic study. Rev. Soc. Esp. Dolor [online]. 2006, vol.13, n.2, pp.81-95. ISSN 1134-8046.

Aim: The goal of this cross-sectional evaluation was to assess pain impact on sleep and symptoms of depression and anxiety in patients with neuropathic pain (NeP). Methods: Participants in an observational, prospective and multicenter study (DONEGA study) with NeP of broad etiologies, completed the Short Form-McGill Pain Questionnaire (SF-MPQ), the COVI Anxiety Scale, the RASKIN Depression Scale, and the MOS Sleep Scale at baseline. Results: A total of 1,519 patients above 18 years [mean ± SD; 56.9±13.6 years old (61.2% female)] with NeP for 1.1±2.8 years were enrolled in the study. Average present pain intensity was 2.8±1.0 (range 0-5) and mean pain past week was 71.2±18.9 mm (range 0-100). Pain substantially interfered with patient normal sleep and its attributes, obtaining high scoring in composite measures (9-items); 47.1±21.3 (range 0-100). The 19.7% and 12.9% of patients had symptoms of depression and anxiety, respectively. Severity of previous and present pain were the most important determinants causing negative impact on patient sleep. Scoring on sleep scale and, alternately, depression and anxiety scales scoring were the main determinants for depression and anxiety, respectively. Conclusions: NeP negatively impact on patient sleep and its attributes, while causes a substantial proportion of patients with symptoms of anxiety and depression. Pain severity amplifies these findings.

Keywords : neuropathic pain; standard condition of care; anxiety; depression; sleep; sleep attributes.

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