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Revista de la Sociedad Española del Dolor

Print version ISSN 1134-8046

Abstract

FIGUEIREDO GONZALEZ, O. et al. Do low ketamine doses complement the paravertebral block?. Rev. Soc. Esp. Dolor [online]. 2016, vol.23, n.5, pp.218-221. ISSN 1134-8046.

Objective: Breast cancer is the most frequent malignant tumor among women in the development world. In Spain, they are diagnosed around 16,000 cases/year, with peak incidence between con 45-65 years old. Our objective was to evaluate the effectiveness of additional low ketamine doses to complement the postoperative analgesia provided by the paravertebral block in breast cancer surgery. Material and methods: Cohort, retrospective, descriptive and observational study of 62 patients undergoing oncologic surgery of breast to wich we performed paravertebral blockade by triple puncture in the lower end of the transverse processes of T2-T4-T6. A group was added intravenous ketamine at low doses and the other nothing. We sedated them with propofol in continuous perfusion by pump and we collected the need of postoperative analgesia in the 72 h after surgery. Results: It was concluded that the addition of low-dose ketamine decreased the need for postoperative analgesia in the 72 hours after the surgery being statistically significant at 48 to 72 hours (p < 0,05). Conclusion: The addition of low doses of ketamine to thoracic paravertebral blockade with triple puncture was able to reduce pain relievers demanded by the patient in the 72 hours after surgery. Limitations of the study were the non utilization of EVA to measure the need for postoperative analgesia and the administration of analgesia scheduled in the first 24 postoperative hours (paracetamol, nonsteroidal anti-inflammatory or paracetamol + nonsteroidal anti-inflammatory).

Keywords : Breast cancer surgery; thoracic paravertebral block; ketamine.

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