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Cuadernos de Medicina Forense
On-line version ISSN 1988-611XPrint version ISSN 1135-7606
Abstract
BLANCO PAMPIN, J.; VARELA GOMEZ, M. and ROMAN RODRIGUEZ, J.L.. Histopathological changes in myocardial necrosis through fibronectin expression. Cuad. med. forense [online]. 2014, vol.20, n.4, pp.170-179. ISSN 1988-611X. https://dx.doi.org/10.4321/S1135-76062014000300003.
The main objective of the study was the application of immunohistochemical techniques in the diagnosis of myocardial ischemia in the early stages with a greater margin of assuredness. We have selected cases of sudden cardiac death in adults, making a descriptive and semiquantitative assessment of the findings. Histopathological diagnosis by inmunohistochemical techniques using fibronectin antibodies has shown higher sensitivity than routine techniques. The satisfactory results as well as well as the simplification of the technique contributes to its implementation in forensic laboratories and application in an important number of forensic cases.
Keywords : Forensic pathology; Sudden cardiac death; Myocardial ischemia; Microscopic diagnosis; Fibronectin.