Abstract

OLAGUIBEL, J.M. et al. New techniques in the study of asthma. Anales Sis San Navarra [online]. 2003, vol.26, suppl.2, pp.57-63. ISSN 1137-6627.

Asthma is a chronic inflammatory disease of the airways that is functionally characterized by variability of lung function and bronchial hyper-responsiveness. Its diagnosis and management is commonly hampered by the lack of objective parameters. This article reviews additional techniques for evaluating both, lung function (bronchial challenge with adenosin-monophosphate, lung resistance measurement by either the impulse oscillometry system or whole body pletismography) and bronchial immuno-inflammatory response (induced sputum, condensates of exhaled air, monitoring of nitric oxide in exhaled air), as well as our experience with them.

Keywords : Asthma; Inflammation; Adenosin-monophosphate; Impulse oscillometry system; Whole body pletismography; Induced sputum; Nitric oxide; Condensates of exhaled air.

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