Abstract

GARCIA LUZARDO, M.R.; RODRIGUEZ CALCINES, N.  and  COLINO GIL, E.. Benign transient hyperphosphatasemia of infancy: a condition to be considered. Rev Pediatr Aten Primaria [online]. 2011, vol.13, n.49, pp.107-111. ISSN 1139-7632.

Benign transient hyperphosphatasemia of infancy (BTHI) is a condition where disproportionately high levels of serum alkaline phosphatase are observed, without clinical or biochemical evidence of bone, liver, renal or metabolic disease. We report a case of an eight months old patient presenting with fever and important increase of serum alkaline phosphatase. The HTBI is a frequent entity to be considered in order to avoid unnecessary investigations. If a patient has high alkaline phosphatase level, with physical examination, calcium, phosphate and liver normal profile, he/her should be monitored clinically and by measuring alkaline phosphatase levels until normalization. If high level persists after 3 months, the origin of the isoenzymes and a family study should be investigated.

Keywords : Hyperphosphatasemia; Alkaline phosphatase.

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