Abstract

DE FREITAS REGO BEZERRA, C.; LUZ DE AQUINO, A.R.; COSTA DE LIMA, K.  and  DA FONTE PORTO CARREIRO, A.. Ultra-sensible C-reactive protein in patients with and without chronic severe generalized periodontitis. Avances en Periodoncia [online]. 2009, vol.21, n.3, pp.145-155. ISSN 2340-3209.

Introduction: The high sensitivity C-reactive protein (hsCRP) constitutes an inflammatory mediator used as predictor of cardiovascular risk that comes being researched as indicative relation factor between cardiovascular and periodontal diseases. This work had the purpose of compare seric levels of C-reactive protein between patients with and without chronic severe generalized periodontitis. Material and methods: A cross-sectional study was realized using a sample with 60 patients, being 29 participants carriers of periodontal diseases (Group I) and 31 without periodontal diseases (Group II). As inclusion criteria were selected patients with diagnosis of chronic severe generalized periodontitis. The research consisted of two stages, clinc and biochemical. The stage was constituted of periodontal examination and the biochemist stage, of the blood collection for determination hsCRP levels and a hemogram. Results: Periodontal disease group presented a average of 0,36 mg/dL, while the group without disease presented 0,17 mg/Dl (p = 0,061). The cardiovascular risk for the group I was classified high for 27,6% of participants and low for 72,4% of them. In the group II, 6,45% presented high risk e 93,5% low risk, being this relation significant statistically gotten for Fisher's Test (p = 0,042) presenting OR = 5,33; IC = 95% (1,02-27,4). The independents variables researched do not presented significant statistically association with the levels of hsCRP. Conclusion: The study indicated that despite of carriers patients of periodontal diseases do not present differents seric levels of hsCRP from the other group, the periodontal disease was considered as risk factor for hsCRP levels elevation.

Keywords : C-reactive protein; periodontitis; cardiopathy.

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