Abstract

SANCHEZ-ORO GOMEZ, Raquel; VILLARIN CASTRO, Alejandro; HERNANDEZ SANZ, Azucena  and  MARTINEZ ARRIBAS, Rocío. Can a relationship between FRAX^® indices and QFracturescores^TM be established?. Rev Clin Med Fam [online]. 2012, vol.5, n.3, pp.166-175. ISSN 2386-8201.  https://dx.doi.org/10.4321/S1699-695X2012000300004.

Objective: To establish a correlation between the values of fracture risk obtained by FRAX^® and QFracturescores^TM tools. Design of the study: Retrospective observational study Location: Speciality Centre in Toledo. Participants: Patients with osteoporosis from a Bone Metabolism consultation. Measurements: Review of clinical history, with data obtained from the moment the antiosteoporotic treatment was commenced, applying FRAX^® risk indices, with and without densitometry (in the cases affected by it) and QFracturescores^TM, and establishing a correlation between them. Results: 99 patients (88,9% female) average age (± standard deviation) 62,3 ± 9,3 years. The average FRAX^® value without densitometry was 7,37 ± 6,33 for major osteoporotic fracture (MOF) and 2,6 ± 3,71 for hip fracture (HF). With densitometry (n=74), the values were 8,6 ± 7,35 and 3,36 ± 4,64, respectively. A 10 year risk with QFracturescores^TM was 4,56 ± 2,83 for MOF and 1,58 ± 1,91 for hip fracture. 37,4% showed a FRAX^® (MOF / HF) ≥ 20% / 3% index. The correlation between FRAX^® and QFracturescores^TM for MOF was 0,751 (IC95% 0,620-0,882) and HF, 0,771 (IC95% 0,645-0,897), getting lower when densitometry values are included [r=0,573 in MOF (IC95% 0,384-0,762) and r=0,487 in HF (IC95% 0,286-0,688)]. Conclusions:FRAX^® and QFracturescores^TM indices show a moderate to strong correlation, especially if densitometry values are not included. Its use can be recommended in primary health care, above all in order to assess the risk of osteoporosis. We do not currently have a reliable benchmark to take diagnostic and therapeutic decisions in our environment.

Keywords : Osteoporosis; Risk Assessment; Risk Factors.

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