Abstract

SANCHEZ-SANZ, B; GARCIA-MUNOZ, C; ALONSO-PEREZ, L  and  FERRARI-PIQUERO, JM. Very early onset inflammatory bowel disease remission induced with oral gentamicin and vancomycin. Rev. OFIL·ILAPHAR [online]. 2022, vol.32, n.2, pp.203-205.  Epub Feb 13, 2023. ISSN 1699-714X.  https://dx.doi.org/10.4321/s1699-714x2022000200014.

Very early onset inflammatory bowel disease occurs in children under 6 years age. It is frequently associated to a diverse ethiology, dysbiosis being usually described as a triggering factor. Commonly, this population is highly resilient to inmmunosuppressant therapies.

We report here a medical case of a patient diagnosed with unclassified and steroid-dependent colitis, with a year of evolution, who had no responded to intensified therapy at home, and, therefore, was hospitalized at our centre. Treatment with oral antibiotics was intended as remission induction in combination with his usual inmmunomodulator treatment. Although clinical remission was observed at first stage, a new activity outbreak emerged requiring a second round of antibiotics therapy, which was unsuccessful and currently withdrawned.

Keywords : Inflammatory bowel disease; vancomycin; gentamicin.

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