Abstract

SAINZ-AJA GUERRA, J.A. et al. Study of the microstructure of femoral patients with hip osteoarthritis and hip fracture by microCT. Rev Osteoporos Metab Miner [online]. 2016, vol.8, n.2, pp.75-81. ISSN 2173-2345.

Whereas bone mineral density (BMD) is characteristically low in osteoporosis, it has been postulated that in osteoarthritis BMD is increased. We aimed to check this concept by analyzing bone volumen and structure in the femoral heads of patients with hip fractures (n=10) and with hip osteoarthritis (n=9). Unexpectedly, the analysis of microstructural parameters by microCT did not reveal significant differences between both groups. In addition, we did not find a significant decline in the trabecular bone volume across the age range studied. These results suggest that the evolution of the trabecular bone of the femoral head is different from the age-related decrease of bone mass in other regions of the skeleton. Elucidating the mechanism involved could suggest new approaches to treat the bone loss associated with aging.

Keywords : hip fracture; osteoarthritis; microCT; microstructure.

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