Abstract

HIDALGO-BLANCO, Miguel Ángel; ANDREU-PERIZ, Dolores  and  MORENO-ARROYO, Mª Carmen. COVID-19 in renal patient. Brief Review. Enferm Nefrol [online]. 2020, vol.23, n.2, pp.122-131.  Epub Oct 05, 2020. ISSN 2255-3517.  https://dx.doi.org/10.37551/s2254-28842020013.

In December 2019, a new subspecies of coronavirus was identified in China, which was named SARS-CoV-2, responsible for the disease that WHO called COVID-19. The disease has spread rapidly causing a global pandemic.

Much is still unknown about SARS-CoV-2, but the first findings support the hypothesis that the severity of COVID-19 is conditioned by the hyperinflammatory response, which occurs in our body after contacting SARS-CoV-2. The severity of the symptoms is conditioned by the respiratory failure caused, however there are studies that are not limited to lung involvement. Evidence suggests that the access mechanism of the SARS-CoV-2 virus is closely related to the ACE2 enzyme. An enzyme that, among other tissues, can be found in the epithelium of renal tubular cells. For this reason, there are data on patients with COVID-19 who are severely affected in kidney function and may have acute kidney failure (a poor prognostic factor).

For this reason, together with the fact that the comorbidities associated with a higher mortality during COVID-19 infection are common in patients with chronic kidney disease, it is necessary to know the available evidence on this matter.

Keywords : D-19; SARS-CoV-2; Kidney disease; Dialysis; Kidney transplant; Review.

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