Abstract

RAYO-MADRID, Juan I et al. Radioguided parathyroid surgery with ¹⁸FCH. Myth or reality. Rev. ORL [online]. 2022, vol.13, n.2, pp.147-158.  Epub Nov 21, 2022. ISSN 2444-7986.  https://dx.doi.org/10.14201/orl.27450.

Primary hyperparathyroidism (PHPT) is the main cause of hypercalcemia in non-hospitalized patients, being caused in 85-90% of cases by a solitary adenoma. Radioguided parathyroid surgery (RGPS), as a GOSTT (Guided intraOperative Scintigraphic Tumor Targeting) technique, uses SPECT-TC with 99mTc-MIBI as the technique of choice. PET-TC with 18F-Choline (18FCH) can be used in patients with negative 99mTc-MIBI, obtaining sensitivities close to 95%. The use of 18FCH in CRGP is very complex, recommending the use of other tracers such as 99mTc-Macroaggregates (99mTc-MAA) or Iodine-125 seeds (125I-Seed). RGPS reduces surgical time, hospital costs and patient morbidity, with high effectiveness and efficiency.

Keywords : minimally invasive surgery; radioguided surgery; parathyroid; hyperparathyroidism; Choline; PET-TC.

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