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Journal of Negative and No Positive Results

On-line version ISSN 2529-850X

Abstract

LOPEZ RUBIO, María Antonia; TARRAGA LOPEZ, Pedro Juan; MELERO LOPEZ, Jesús Alberto  and  MOYA PLAZA, Andrés. Sexual health in women with breast cancer treated with Tamoxifen. JONNPR [online]. 2020, vol.5, n.12, pp.1528-1537.  Epub Dec 18, 2023. ISSN 2529-850X.  https://dx.doi.org/10.19230/jonnpr.3982.

Breast cancer can alter certain components of sexual function due to the disease and the treatments used.

Objetive.

To analyze if patients with breast cancer treated with Tamoxifen have sexual dysfuntion.

Method.

Cross-sectional, observational study to detect sexual dysfunction in patients with breast cancer with Tamoxifen treatment and compare it with general population. The cases of breast cancer at Virgen de La Luz Hospital from April 2015 to April 2016 have been analyzed, selecting women in treatment with tamoxifen, under 50 years and sexually active, applying a sexual health questionnarie and comparing them with general population.

Results.

130 breast cancers were diagnosed, 34 were susceptible to study (26,15%). Seven patients (20,6%) participated, with a mean age of 42,7 years (35-50) and stable partner in 85,7%. Moderate disorders of sexual desire have been observed in 28,6% and in arousal in 14,28%, as well as lack of sexual initiative in 42,86%, disorder of vaginal lubrication in 28,6% and problems with vaginal penetration in 14,3%, but overall they are satisfied with their sexual activity. Comparing with general population, it´s striking that 14,2% of the last show some degree of sexual insatisfaction.

Conclusions.

There are no significant differences regarding sexual dysfunction, although there may be greater anticipatory anxiety, sexual desire dysfunction and vaginal lubrication in the Tamoxifen group, which probably do not reach statistical significance due to sample size.

Keywords : Sexual Health; Women; Breast Cancer; Tamoxifen; Sexuality; Breast; SERM.

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