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Anales de Medicina Interna
versión impresa ISSN 0212-7199
Resumen
ABELLAN MARTINEZ, Mª. C. et al. Pulmonary histiocytosis X: A case report and literature review. An. Med. Interna (Madrid) [online]. 2002, vol.19, n.1, pp.16-18. ISSN 0212-7199.
Histiocytosis X or Langerhans cell histiocytosis is an unfrequent disease, which consists on proliferation of Langerhans cells. The etiology is unknown. Diagnosis is reached by electron microscope study of the biopsy, in which the Birbeck intracitoplasmatic granules of the Langerhans cells are found and/or by inmunohistochemistry procedures able to detect S-100 antigen and CD1 cells. Diagnosis can also be reached with a bronchoalveolar lavage in which CD1 cells will appear in a score higher than 5%. We present the case of a 16 year-old girl that first appeared with a pulmonar lesion with a honey comb X-ray pattern and unsintomatic mandibular bone affectation. Diagnosis was reached by biopsy study using S-100 antigen detection procedures. We consider this case an important one due to the unfrequency of this particular disease.
Palabras clave : Histiocytosis; Langerhans cells; Eosinophilic granuloma.