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Revista Española de Enfermedades Digestivas
versão impressa ISSN 1130-0108
Resumo
HERRAIZ, M. e MUNOZ-NAVAS, M.. Recognition and management of hereditary colorectal cancer syndromes. Rev. esp. enferm. dig. [online]. 2009, vol.101, n.2, pp.125-132. ISSN 1130-0108.
Over 1.900 colorectal tumors will arise in association with a hereditary colorectal cancer syndrome in Spain in 2009. The genetic defects responsible for the most common syndromes have been discovered in recent years. Genetic testing helps diagnose affected individuals and allows identification of individuals at-risk. Colonoscopy and prophylactic colectomy decrease colorectal cancer incidence and overall mortality in patients with hereditary colon cancer. Extracolonic tumors are frequent in these syndromes, so specific surveillance strategies should be offered.
Palavras-chave : Familial adenomatous polyposis; Lynch syndrome; MYH-associated polyposis; Hereditary colon cancer.