SciELO - Scientific Electronic Library Online

 
vol.13 número4Neuropatía periférica tras el parto: Implicaciones de la anestesia epiduralIntervenciones del psicólogo en las Clínicas del Dolor: Una propuesta desde la experiencia de la Unidad del Dolor del Hospital Universitario Príncipe de Asturias en Alcalá de Henares, Madrid índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Não possue artigos similaresSimilares em SciELO
  • Em processo de indexaçãoSimilares em Google

Compartilhar


Revista de la Sociedad Española del Dolor

versão impressa ISSN 1134-8046

Resumo

VILLAR, J.. How to investigate a subject so subjetive as pain. Rev. Soc. Esp. Dolor [online]. 2006, vol.13, n.4, pp.250-253. ISSN 1134-8046.

About 10 million people in Spain suffer from chronic pain. Despite the identification of important steps in the mechanisms of pain, an unacceptably large number of people live with it chronically. Since Melzack and Wall framed the idea of the central nervous system filtering, assessing and modulating the sensory information with their gate-control theory in 1965, we have advanced our understanding of the pain process. In this paper, I review the pathophysiological and molecular bases of pain, and explain the reasons why we do not have the tools to adequately treat all chronic or acute pain. Of the current 100 clinical trials of pain relievers conducted by investigators from the National Institutes of Health in the United States, most of them are investigating new ways to deliver old standards or alternative approaches. With the help of the new science of genomics, we are discovering that there are genetic differences among individuals in response to drugs.

Palavras-chave : Pain; nociception; morphine; analgesia; neuropathy; "gate-control" theory.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )

 

Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons