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Pediatría Atención Primaria
versão impressa ISSN 1139-7632
Resumo
LEGANES VILLANUEVA, Carlos et al. Neuroleptic malignant syndrome in pediatrics. A case report. Rev Pediatr Aten Primaria [online]. 2021, vol.23, n.89, pp.71-74. Epub 09-Maio-2022. ISSN 1139-7632.
Abstract
Neuroleptic malignant syndrome is a pediatric emergency with high morbidity and mortality, related to an alteration of the dopaminergic neurotransmission system. It is characterized by hyperthermia along with muscular hypertonia, dysautonomia, and altered level of consciousness.
An early diagnosis is essential to prevent common complications such as bronchoaspiration, wear, bedsores, infectious processes, and neuropsychiatric changes. Treatment should include general support measures and symptomatic pharmacological therapy.
Although most of the cases described correspond to the adulthood, it has also been described in children and adolescents. We present a case of neuroleptic malignant syndrome in a 12-year-old adolescent with encephalopathy and spastic tetraparesis secondary to the cessation of baclofen administration.
Palavras-chave : Dopamine; Hypertonia; Neuroleptic; Neuroleptic malignant syndrome.