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Pediatría Atención Primaria
versão impressa ISSN 1139-7632
Resumo
OCHOA-SANGRADOR, Carlos e GIMENO-DIAZ-DE ATAURI, Álvaro. Bronchodilators in bronchiolitis: should we reassess their selective use?. Rev Pediatr Aten Primaria [online]. 2021, vol.23, n.91, pp.317-320. Epub 06-Fev-2023. ISSN 1139-7632.
Authors' conclusions
compared to guidelines‐guided strategy, treating infants with viral bronchiolitis using the phenotypic‐guided bronchodilator therapy strategy is a more cost‐effective strategy, because it involves a lower probability of hospital admission at lower total treatment costs. Randomized controlled trials using biomarkers to stratify patients most likely to respond to bronchodilators are necessary.
Reviewers' commentary
the available information does not seem sufficient to make changes to the current recommendations in acute bronchiolitis management. There is still need for a predictive model that allows to identify potential responders to bronchodilators, as well as a clinical trial with a sufficient sample size to estimate the effectiveness of the strategy of its selective use.
Palavras-chave : Bronchiolitis; Bronchodilators; Costs and cost analysis.