Meu SciELO
Serviços Personalizados
Journal
Artigo
Indicadores
- Citado por SciELO
- Acessos
Links relacionados
- Citado por Google
- Similares em SciELO
- Similares em Google
Compartilhar
Revista de Diagnóstico Biológico
versão impressa ISSN 0034-7973
Resumo
VARONA, J.; ESCRIBANO, E. e MARTIN-CALDERON, JL.. Fenobarbital: farmacocinética, toxicología y monitorización por el Laboratorio. Rev Diagn Biol [online]. 2001, vol.50, n.1, pp.13-16. ISSN 0034-7973.
Phenobarbital is an antiepileptic agent widely used for treatment partial and generalised tonic-clonic seizures. Its narrow therapeutic range and its high ability for depressing central nervous system together with its capacity to produce enzymatic self-induction make that it is one of the most frequently drugs monitored at clinical laboratory. In this work we review pharmacological proprieties of the phenobarbital, studying in addition pharmacokinetics, adverse reactions due to poisoning, the indications of monitoring and analytical methods used for its measure at clinical laboratory.
Palavras-chave : phenobarbital; pharmacokinetics; Therapeutic monitoring; antiepileptic; plasma levels; barbiturates.