Actas Urológicas Españolas
versión impresa ISSN 0210-4806
SANCHEZ-CARBAYO, M.. Use of antibodies arrays in the study of bladder cancer. Actas Urol Esp [online]. 2007, vol.31, n.9, pp.1082-1088. ISSN 0210-4806.
Antibodies arrays represent a very versatile high-throughput technology that enables multiple protein detection simultaneously. It allows quantifying protein levels multiparametrically, and analyzing their post-translational modifications, thus improving the funtional characterization of molecular processes associated with neoplasic diseases. Moreover, the identification of protein expression patterns characteristic of tumor progression and of different tumor subtypes can improve the clinical management of patients with bladder cancer. In the near future, they may allow establishing tailored therapies according to the aggresiveness of each specific tumor.
Palabras clave : Antibody arrays; Bladder cancer; Proteomics.