Resumo

MARTINS, M.ª Salete F. et al. Rice bran supplementation during nutritional recovery period of malnourished rats improves colon development. Nutr. Hosp. [online]. 2007, vol.22, n.6, pp.648-653. ISSN 1699-5198.

Objective: To investigate the colon's development in rats subjected to protein energy malnutrition followed bysupplementation with rice bran. Materials and methods: Weaned Wistar male rats (21 days old), weight (40-50 g) were divided into two groups: diet with 17% protein (C; control group) or an aproteic diet (A; aproteic group), for 12 days. After this, 50% of the rats from each group were sacrificed. The remaining rats were further distributed in the three groups for a recovery (21 days): control (C) continued to receive the control diet whereas the aproteic group (A) received either a control diet (AC) or a control diet supplementedwith 5% of rice bran (ARB). Results: The A group showed alterations in the colon and cecum, excreted dry feces mass and fecal nitrogen, compared with C rats. In the proximal colon of A rats, the external muscularis and the width of the colon wall were higher whereas in the distal colon they were lower than C. After the recovery period, the relative cecum mass, colon mass and colon length of the recovered groups (AC and ARB) were higher than in the C group. Dry feces and fecal nitrogen excreted of the rats from recovered groups were lower than C group. Colon length of the AC group was lower than in the C group. Only the crypt's depthfrom ARB group was higher than in the C group. Conclusion: Control diet supplemented with 5% rice bran, reestablished the large intestine of aproteic rats. The recovery in the ARB group was even better than in the AC rats.

Palavras-chave : Colon; Morphology; Malnutrition; Recovery; Rice bran.

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