SciELO - Scientific Electronic Library Online

 
vol.28 número3Determinantes de la variación del peso postparto en una cohorte de mujeres adultas: un enfoque jerárquicoUtilidad de los datos antropométricos auto-declarados para la evaluación de la obesidad en la población española: estudio EPINUT-ARKOPHARMA índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google

Compartir


Nutrición Hospitalaria

versión On-line ISSN 1699-5198versión impresa ISSN 0212-1611

Resumen

TURSI RISPOLI, Leonardo De et al. Oxidative stress: a comparative study between normal and morbid obesity group population. Nutr. Hosp. [online]. 2013, vol.28, n.3, pp.671-675. ISSN 1699-5198.  http://dx.doi.org/10.3305/nh.2013.28.3.6355.

Objective: To determine the level of oxidative stress in morbid obese patients by comparing their results to those of a normal population. Material and methods: We have studied the metabolites most representative of OS, both in the blood (MDA, 8-oxo-dG, GSSG and the ratio GSSG/GSH) and in the urine (8-oxo-dG), as well as the GSH antioxidant. A descriptive analysis of the sample was performed. The Kolmogorv-Smirnov test was used to assess whether the distribution of the different metabolites was normal. In the case of normal distribution, the Student's t test was used to compare the means, the Mann-Whitney U test was used for non-parametric data, with a significance level of p < 0.05 for hypothesis contrast. Results: There were 28 patients in each group, without statistically significant differences regarding age and gender. The group of patients with morbid obesity presented an average BMI of 50.1 ± 4 and 23.9 ± 6 in the group with normal weight. 67.8% of the patients with morbid obesity had other comorbidities. There were no associated pathologies in the control group. All the values for the different OS metabolites were higher in the group of patients with morbid obesity than in the control group, whereas the activity of the antioxidant systems (GSH) was lower in the group with morbid obesity. Conclusion: The figures of OS metabolites obtained in the group of patients with morbid obesity confirm the presence of OS in obesity at a pathological level given the differences obtained in the group of normal population.

Palabras clave : Obesity; Morbid obesity; Oxidative stress; Free radicals; Antioxidants.

        · resumen en Español     · texto en Español     · Español ( pdf )

 

Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons