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Nutrición Hospitalaria

On-line version ISSN 1699-5198Print version ISSN 0212-1611


CORTES CASTELL, E. et al. Correspondence between the fatty acids in healthy children serum and in membrane phospholipids. Nutr. Hosp. [online]. 2013, vol.28, n.5, pp.1541-1545. ISSN 1699-5198.

Introduction: The diet is important in the supply of fatty acids in humans, especially those of the n-3 and n-6 families by its essentiality and related physiological function. It is important to have reference values in accessible biological samples: serum and erythrocyte membranes, in order to alleviate potential shortfalls. The objective is quantifying fatty acids present in these samples from C6 to C26. Material and methods: the determinations of the fatty acids of 30 healthy children in serum and its corresponding membrane phospholipids from blood cells by lipid extraction, methylation, separation and quantification in gas chromatography with detection of masses have been. It is comparing the values obtained in each serum and its partner of cell membranes. Results and discussion: It is have obtained normal values in healthy children. The C16, which represent a quarter of all fatty acids, it is in the same proportion in both samples, in the rest of fatty acids, there is no clear correspondence between both values. In the n-6 family, the C18:2n6 is higher in serum against the C20:4n6 which is in the phospholipids. In the same way between the n-3 family, the C20:5n3 is higher in serum and the C22:6n3 is in membrane phospholipids. These values are cause of different processes, recent nutritional contribution to serum and with long-term implications and metabolic values in the phospholipids of membranes.

Keywords : Fatty acids; Polyunsaturated; Serum; Membrane phospholipids; Reference values.

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