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Nutrición Hospitalaria

On-line version ISSN 1699-5198Print version ISSN 0212-1611


BACARDI GASCON, Montserrat; JIMENEZ MORAN, Elsa; SANTILLANA MARIN, Ernestina  and  JIMENEZ CRUZ, Arturo. Effect of pre and post natal undernutrition on components of metabolic syndrome later in life: systematic review. Nutr. Hosp. [online]. 2014, vol.29, n.5, pp.997-1003. ISSN 1699-5198.

Background: A fetal environment or postnatal undernutrition, might become risk factors that increase susceptibility for chronic-degenerative diseases later in life. Fetal programming means that during prenatal period adverse environment might increase the susceptibility for metabolic changes later in life. Objective: The purpose of this study was to analyze the effect of pre-and postnatal malnutrition in the presentation of obesity and components of metabolic syndrome (MS) later in life. Methods: A literature electronic search on PubMed and EBSCO was conducted. The following term was searched: "Undernutrition in early life and obesity", from studies published from November 1997 through January 2014. Seven studies were identified, and six more were included from other references. Results: We analyzed thirteen publications form six studies conducted in six countries from Asia, Africa, Europe and Latin America. Ten of the studies were retrospectives and the age ranged from 11 to 70 years old. In all studies an association of pre or postnatal undernutrition with components of MS later in life was observed. Conclusion: This review shows a consistent association between prenatal and postnatal undernutrition with one or more MS components later in life.

Keywords : Undernutrition; Metabolic syndrome; Prenatal factors; Postnatal factors; Systematic review.

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