SciELO - Scientific Electronic Library Online

vol.31 issue6A home and ambulatory artificial nutrition (NADYA) Group Report, Home Parenteral Nutrition in Spain, 2013Adipose tissue redistribution caused by an early consumption of a high sucrose diet in a rat model author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Nutrición Hospitalaria

On-line version ISSN 1699-5198Print version ISSN 0212-1611


PALMISCIANO BEDE, Teresa et al. Effect of the intake of liquids rich in polyphenols on blood pressure and fat liver deposition in rats submitted to high-fat diet. Nutr. Hosp. [online]. 2015, vol.31, n.6, pp.2539-2545. ISSN 1699-5198.

Introduction: seeking better quality of life, the number of studies on functional foods and disease prevention is growing fast. Whole red grape juice (WRGJ) and red wine (RW) stand out, which are rich in polyphenols, showing antioxidant and anti-inflammatory activity. Objective: to evaluate the effect of WRGJ and RW intake and resveratrol solution (RS) on blood pressure and fat liver deposition of rats fed with high-fat diet. Material and Methods: during 60 days, 50 Rattus norvegicus Wistar Albino adults were divided into: control group (CG) - balanced diet, hyperlipidic group (HG), red wine group (RWG), grape juice group (JGG) and resveratrol group (RG) - hyperlipidic diet. Feed and water were offered ad libttum to all groups. WRGJ, RW and RS were offered daily to JG, WG and RG, respectively. Blood pressure was measured using tail plestimograph. The animals were anesthetized, sacrificed and the liver was removed, weighed and fat was extracted using Soxhlet extractor. Results: no difference in weight gain, feed intake, liver weight and diastolic blood pressure among groups was observed. However, systolic blood pressure (mmHg) and liver fat concentration (g%) were lower (p <0.05) in JGG than in HG, WG and RG, but similar to CG. Conclusions: the daily consumption of WRGJ minimizes the effects of high-fat diet on systolic blood pressure and prevents nonalcoholic fatty infiltration in the liver of animals, which was not observed in the consumption of RW or resveratrol solution.

Keywords : Polyphenols; High-fat diet; Blood pressure; Fatty liver; Wistar rats.

        · abstract in Spanish     · text in English     · English ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License