SciELO - Scientific Electronic Library Online

vol.32 issue6Efficacy of self-monitoring in weight loss: a systematic review of randomized controlled studiesMaternal diabetes mellitus and its impact on child neurodevelopment: systematic review author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Nutrición Hospitalaria

On-line version ISSN 1699-5198Print version ISSN 0212-1611


LUIS, D. A. de; IZAOLA, O.  and  ALLER, R.. Assessment of the genetic modification inducing diet through blood mononuclear cells. Nutr. Hosp. [online]. 2015, vol.32, n.6, pp.2478-2483. ISSN 1699-5198.

The term nutrigenomics was created to describe how nutrition affects genes and the functions of the protein, at the transcriptional level, proteomic, and metabolic. Using changes in gene expression in blood mononuclear cells could be a model to assess the dietary intervention studies in order to understand the underlying mechanisms and impact of diet and nutrients in atherosclerosis, resistance insulin, obesity and diabetes mellitus. There are studies that have changed the dietary intake of cholesterol, polyunsaturated fat, monounsaturated, antioxidants and decreased caloric intake showing a variety of effects on the expression of mRNA in blood mononuclear cells related to inflammation, immunity, lipid metabolism genes, etc. These molecular findings entrench awareness of our body's response to diet and open up the possibility of rapid analysis of new diagnostic pathways in this area of knowledge and even new therapeutic tools.

Keywords : Gene expression; RNAm; Nutrigenomics; Blood mononuclear cells.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License