Abstract

MONZO CASTELLANO, E.; MORALES SUAREZ-VARELA, M.; MAYANS FERRER, J.  and  VILA LOPEZ, V.. Clinical characteristics of patients with non-Hodgkin lymphoma (NHL) in Arnau de Vilanova Hospital Valencia, Spain. An. Med. Interna (Madrid) [online]. 2001, vol.18, n.12, pp.629-634. ISSN 0212-7199.

Objective: To define the clinical characteristics of patients with non-Hodgkin lymphoma (NHL) in general and by histological subtypes based on the REAL classification.  Patients and methods: From a total of 210 case histories of patients with NHL, 188 presenting a complete pathology report were selected. The latter was either based on the REAL classification or was converted to it by an expert. The clinical features of the patients at the time of diagnosis were also recorded.  Results: Significant differences were observed in the distribution by sex among mantle cell lymphomas, with a predominance among males (p= 0.005). The youngest patients were diagnosed of Burkitt lymphoma and B lymphoblastic lymphoma. Patient status improved significantly (p= 0.0001), with a predominance of ECOG 0, and the stage of the patients studied was 74.1% (stage III/IV) versus 25.9% (stage I/II).  Conclusions: The different characteristics of patients with NHL suggest the need for a single classification with diagnosis by histological subtype.

Keywords : Non-Hodgkin lymphoma; Clinical characteristics; REAL classification.

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