Abstract

BAUZA ALONSO, A. et al. Idiopatic mediastinal fibrosis in association with hypercoagulability state: A case report . An. Med. Interna (Madrid) [online]. 2001, vol.18, n.12, pp.638-640. ISSN 0212-7199.

Mediastinal fibrosis is a rare and unknown disease characterized by the presence of a fibrotic mass in the anterior mediastinum that can invade close structures as gullet, trachea, recurrent nerve, superior cava vein etc. Only 1-2% of patients with mediastinal fibrosis associate superior cava vein obstruction. When it appears, it is produced by extrinsic compression for fibrotic magma in almost all the cases. A case of hypercoagulability disorder associated with mediastinal fibrosis and superior cava vein obstruction by thrombosis (intrinsec mechanism), and the satisfactory evolution after the treatment with oral anticoagulation, corticosteroids and tamoxifen is presented. 

Keywords : Mediastinal fibrosis; Hypercoagulability; Tamoxifen.

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