Abstract

ALAMA ZARAGOZA, Mª A. et al. Hepatic granulocytic sarcoma: an unussual  presentation. An. Med. Interna (Madrid) [online]. 2003, vol.20, n.3, pp.39-42. ISSN 0212-7199.

A case of granulocytic sarcoma (chloroma) of hepatic localization is presented. It is a extramedullary strange tumour, composed of immature precursors of myeloid cells. Clinically it can show, before, during or after a acute myeloid leukemia, chronic myeloproliferative disorders or myelodysplastic syndromes.  Our patient, 81 year-old male, presented a process of important acute jaundice, with negative image thecnics, what indicated us the intrahepatic origin, negative tumorals markers, negative serology and hepatic biopsy (the piece of greenish coloration is described) what showed a hepatic sinusoides diffuse infiltration by indifferentation cellularity, with study immuno-histochemical that was positive for the myeloperoxydase, giving a diagnose compatible with hepatic infiltration for acute myeloid leukemia.  The patient doesn´t present affectation of peripheral blood, and he died for acute hepatic and renal failure after 8 days of entrance.

Keywords : Granulocytic sarcoma (chloroma); Acute myeloid leukemia; Jaundice; Study immuno-histochemical; Extra-medullary myeloid tumour.

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