Abstract

LOZANO PARRAS, M. A. et al. Kikuchi´s disease: a case report and literature review. An. Med. Interna (Madrid) [online]. 2003, vol.20, n.5, pp.31-34. ISSN 0212-7199.

Kikuchi-Fujimoto disease, also known as hystiocytic necrotizing lymphadenitis, is an unusual entity which affects predominantely young asiatic females, although its distribution is world-wide. Cardinal symptoms are fever and adenopathy, generally cervical, although generalized and extraganglionar cases have been described. Considered a self-limiting disease, it has to be differentiated by pa-thologic analysis from other less-benign disorders such as lymphoma or hystiocitoma, which bear worse prognosis and may require specific treatment. Although the origin of this disease is unknown, a viral origin is postulated and the inmune system is involved. Kikuchi disease has been associated to other entities such as subcutaneous lupus erythematosus, Hashimoto thyroiditis, etc…requiring patients be followed inmunologically after diagnois of this disease. We present a case of Kikuchi disease associated with subacute lym-phocytic thyroiditis.

Keywords : Kikuchi disease; Necrotizing lymphadenitis; Cervical lymphadenopathy; Subacute thyroiditis.

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