Resumo

CASTELLANOS-COSANO, L. et al. Association between diabetes mellitus and chronic oral infectious processes of endodontic origin. Av Odontoestomatol [online]. 2011, vol.27, n.5, pp.259-266. ISSN 2340-3152.

The literature provides evidence on the relationship between diabetes mellitus (DM) and two chronic oral infections of high prevalence: periodontal disease (PD) and chronic apical periodontitis. Both infectious processes of the oral cavity share two characteristics: 1) a common gram-negative anaerobic microbiota and 2) increased local levels of cytokines and inflammatory mediators, which may affect the systemic levels. The interaction between DM and chronic oral infections is based in the inflammation-oxidative stress axis. DM is associated to aggressive forms of PD, higher prevalence and greater sizes of periapical lesions, and to worse prognosis for endodontically treated teeth. The results of some studies suggest that apical periodontitis could contribute to metabolic dyscontrol on diabetic patients.

Palavras-chave : Diabetes; endodontics; periodontal disease; apical periodontitis; root canal treatment.

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