Avances en Odontoestomatología
Print version ISSN 0213-1285
JIMENEZ MALAGON, M.C. et al. Oral manifestations in HIV/AIDS patients associated with antiretroviral treatment and immune status in two foundations of Cartagena city. Av Odontoestomatol [online]. 2012, vol.28, n.4, pp.181-189. ISSN 0213-1285.
Objective: The aim of this study was to determine the association between oral manifestations of AIDS patients with antiretroviral therapy and their immune status. Methodology: a cross-sectional study was done in a population of 166 patients from two Cartagena´s city foundations, the information was collected through an intraoral stomatological examination considering the standard for the clinical diagnosis of oral manifestations associated with AIDS established by the Collaborating Centre WHO about oral manifestations of human immunodeficiency virus, information such as viral load, CD4 and antiretroviral therapy were obtained from the medical history. Results: The prevalence of oral manifestations associated with AIDS was 59.5%, candidiasis was the most common oral manifestation with a prevalence of 35.5%, the patients treated with oral monotherapy had fewer events than those treated with combination therapy with statistically significant values, OR: 0.20, CI 0.00-0.96 (p<0.02), pseudomembranous candidiasis as oral manifestations associated with AIDS has less probabilities to occur when patients have CD4 levels above 500 cel./mm3 showing values statistically significant with a OR: 0.297, CI: 0103-0852 (p<0.03). Conclusions: Patients treated with monotherapy as antiretroviral drug therapy presented less oral manifestations than patients treated with dual therapy, about candidiasis, the subtype pseudomembranous candidiasis has less probabilities to occur when you have CD4 levels above 500 cel./mm3.
Keywords : Viral load; antigens CD4; HIV Infections (Mesh Database).