SciELO - Scientific Electronic Library Online

 
vol.25 issue2Haloperidol and risperidone in the treatment of delirium and its subtypesEstimating prevalence of anxiety and mood disorder in survey data using the GHQ12: Exploration of threshold values author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


The European Journal of Psychiatry

Print version ISSN 0213-6163

Abstract

PALMA-SEVILLANO, Carol et al. Randomised controlled trial of cognitive-motivational therapy program for the initial phase of schizophrenia: a 6-month assessment. Eur. J. Psychiat. [online]. 2011, vol.25, n.2, pp.68-80. ISSN 0213-6163.  http://dx.doi.org/10.4321/S0213-61632011000200002.

Background and Objectives: The aim of this study is to investigate the relative effectiveness of routine care (RC) in addition to a specific early intervention program (PIPE) compared to routine care alone. Methods: A total of 34 participants in the initial phase of schizophrenia took part in randomized, single-blind controlled trial. Participants were randomized to receive either routine care (RC; n = 13) or routine integrated with Cognitive-Motivational Therapy (PIPE; n = 21). PIPE comprised individual and family Cognitive-Motivational therapy plus routine care for 12 months. In this paper we present preliminary results at 6 months after the beginning of the intervention. Clinical assessments were carried out at pre-treatment, and in this manuscript the results at 3 and 6 months after starting the intervention by external raters are presented, using the Positive and Negative Syndrome Scale, Brief Psychiatry Rating Scale, the Clinical Global Impression Scale, the Global Assessment of Functioning scale, and relapses. Mann-Whitney test and MANOVAs analysis for variance effects were used for the statistical analysis. Results: Significant greater clinical effects were observed in those patients treated in RC+PIPE at three months from baseline assessment and at six months in PANSS scale (Mann-Whitney test; p < 0.000). Other benefits of the program included increase in global activity, reduced relapse rates, and reduction of the pharmacological treatment. Conclusions: These findings show the effectiveness of a program of routine care integrated with cognitive-motivational interventions (individual and family therapy) over routine psychiatric care alone for patients who are in the initial phase of schizophrenia.

Keywords : Schizophrenia; First-episode; Initial phase; Early intervention.

        · text in English     · English ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License