SciELO - Scientific Electronic Library Online

vol.24 issue2Disparities in the effect of working conditions on health between immigrant and native-born populations in SpainA proposed guideline for economic evaluation of health technologies author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Gaceta Sanitaria

Print version ISSN 0213-9111


CARRACEDO-MARTINEZ, Eduardo  and  PIA-MORANDEIRA, Agustín. Impact of a health safety warning on strontium ranelate utilization. Gac Sanit [online]. 2010, vol.24, n.2, pp.151-153. ISSN 0213-9111.

Objective: To evaluate changes in the use of strontium ranelate following a health safety warning in November 2007 on the risks of the development of DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) with the use of this medicine. Method: Monthly strontium ranelate DHD (daily defined doses/1,000 inhabitants/day) were calculated between 2006 and 2008 in a health area of Spain. The data were analyzed graphically and through a multiple regression model. Results: Graphical representation showed a long-term rising trend throughout the study period, although growth slowed after the safety warning was issued. The multiple regression model showed that the health warning was statistically significant. Conclusion: The use of strontium ranelate continues to grow after the issue of the health safety warning, although at a slower pace than previously.

Keywords : Strontium ranelate; Osteoporosis; Drug utilization.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License