Archivos de la Sociedad Española de Oftalmología
versión impresa ISSN 0365-6691
DE-DOMINGO-BARON, B. et al. Use of topical voriconazole in alternaria keratitis. Arch Soc Esp Oftalmol [online]. 2008, vol.83, n.8, pp.493-495. ISSN 0365-6691.
Clinical case: A 38-year-old man with fungal Alternaria keratitis was referred from another hospital 25 days after post-traumatic penetrating keratoplastia surgery on his right eye. We commenced treatment with topical voriconazole and the condition resolved. Discussion: Fungal Alternaria keratitis is rare, and treatment is difficult because the clinical response does not correlate well with the antibiotic in vitro sensitivity of the fungus. Clinical cases need to be diagnosed and treated quickly if visual loss is to be avoided. The combination of topical and systemic voriconazole has been shown to be an effective treatment for this condition.
Palabras clave : Fungal keratitis; resistent keratitis; topical voriconazole; Alternaria; penetrating keratoplastia.