Abstract

GARCIA-ALVAREZ, C. et al. Ocular retention in patients with uveal melanoma managed by a multimodality approach. Arch Soc Esp Oftalmol [online]. 2009, vol.84, n.3, pp.145-149. ISSN 0365-6691.

Objective: to analyze ocular survival in eyes with uveal melanoma treated with conservative therapies, in a centre that applies all treatment modalities. Methods: Patients diagnosed with uveal melanoma and treated between September 1990 and April 2007 were included in an historical cohorts study. Results: 273 patients were included. 193 were treated with conservative treatments (70.69%) and 80 were enucleated as primary treatment. 14 patients were enucleated after conservative treatment (7.2%). Kaplan-Meier survival analysis showed an 88% survival probability of the eye in the first 5 years after conservative treatment and 83% at 10 years. Conclusions: Conservative treatments for uveal melanoma, especially brachitherapy, are safe and effective in relation to tumor control and rate of secondary effects.

Keywords : Intraocular tumors; uveal melanoma; episcleral brachitherapy; enucleation.

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