Abstract

ANTONIADIS PETRAKIS, N.  and  GONZALEZ ROMERO, T.C.. Use of vitamine C in liposuction tumescent solution as lipolisis and fibrosis inductor: Experimental study. Cir. plást. iberolatinoam. [online]. 2007, vol.33, n.2, pp.105-110. ISSN 1989-2055.

Liposuction does not always let to remove all the amount of adipose tissue which causes lipodistrophy, for that reason, it is recommended the necessity to improve that technique. We try to demonstrate that the use of vitamin C in the tumescence solution induces lipolysis and raises fibrosis. This article is a descriptive, prospective, experimental and comparative research of a sample of 30 mice of Sprague- Dawley type of both sexes, which were infiltrated with a tumescence solution in the subdermic inguinal region with vitamin C to the experimental group and with tumescence solution without vitamin C to the control group, for a further histological macroscopic as well as microscopic study. The results showed that 100% of the samples with vitamin C presented changes in the adipose tissue which suggested lipolysis, whereas 82% were evidence for the formation of young collagen. As a conclusion, vitamin C helps lipolysis and promotes synthesis of collagen when it is used as a part of the tumescence solution in experimental animals.

Keywords : Vitamin C; Tumescente solution; Lipolysis; Fibrosis; Lipodistrophy; Liposuction.

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