Cirugía Plástica Ibero-Latinoamericana
versión impresa ISSN 0376-7892
LASSO, J.M. et al. The state of the adipose-derived stem cell therapies in Plastic Surgery. Cir. plást. iberolatinoam. [online]. 2010, vol.36, n.3, pp.215-221. ISSN 0376-7892.
Over the past decade, cell therapy has emerged as a new approach to reverse several diseases as myocardial ischemia and fistula in Crohn disease; but lately new efforts are centered in breast reconstruction. Several types of adult stem cell have been studied in both preclinical and clinical condition for this purpose: bone marrow cells, circulating cells, and myoblasts. Recently the existence of a population of stem cells located in the adipose tissue has been observed. These cells are able to differentiate into multiple cell lineage including adipocytes and endothelial cells. In this review we discuss the basic principle of adipose-derived stem cell (types, characteristic, harvesting and expansion), the initial experimental studies and the currently ongoing clinical trials.
Palabras clave : Stem cells; Cellular therapy; Adipose tissue.