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Cirugía Plástica Ibero-Latinoamericana

versión On-line ISSN 1989-2055versión impresa ISSN 0376-7892

Resumen

SILVA-GAVARRETE, J.F.; CARDENAS-CAMARENA, L.  y  GUERRERO, M.T.. Topic type A botulinum toxin with iontophoresis in the treatment of armpit hyperhidrosis: effect and persistency. Cir. plást. iberolatinoam. [online]. 2011, vol.37, n.3, pp.301-307. ISSN 1989-2055.  http://dx.doi.org/10.4321/S0376-78922011000300013.

The overproduction of sweat by the exocrine glands is termed Hyperhidrosis (HH) and frequently become a dermatologic and social problem for humans. Nowadays, we have multiple treatments that controls the armpit HH. Botulinum toxin type A (TXB-A) is known to be the best treatment to eliminate this problem but the needing of multiple injections in the armpit limits patients´ acceptance. Clinical iontophoresis method uses galvanic current to introduce many transdermal medications. We perform a simple blind clinical assay over 10 patients with armpit HH in who we apply an inert gel blended with Botulinum toxin type A (TXB-A) Dysport® using one session of iontopheresis in one armpit; in the same moment the other armpit was injected with the toxin in the conventional way. The results where evaluated and compare by Minor Test (starch-iodine test) in each patient at day 10th, 2 months and 5 months after the application. The same number of units and dilution of TXB-A where used in the topic and injected administration way. Results shows a diminished armpit HH in both sides over the whole study, been higher percentage of the effect in the injected way. In general a 74.67% decrease of armpit sweat for the topical way with iontopheresis and 90.33% of decrease of armpit sweat for the injected way. In the 5 months control of the persistency of the effect, both ways of administration of TXB-A reports with statistical significant results. Therefore in the present study we conclude that TXB-A apply topically with iontopheresis improves the armpit HH and shows a persistency of the effect at least for 5 months period.

Palabras clave : Armpit Hyperhidrosis; Botulinum Toxin Type A; Iontopheresis.

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