Abstract

SERNA-CUELLAR, E.  and  SANTAMARIA-SOLIS, L.. Which is the survival of fat grafts on the face? How to quantify it?: evidence based medicine. Cir. plást. iberolatinoam. [online]. 2013, vol.39, suppl.1, pp.s82-s89. ISSN 1989-2055.  https://dx.doi.org/10.4321/S0376-78922013000500017.

Many reports concerning the success of fat auto-grafts in humans are widely subjective or semi-quantitative in best of cases. Even today, additional studies, clinical or basic, are ne-cessary before the value of this technique can be calculated. With the aim of quantifying the survival of fat auto-grafts on the face, a prospective randomized study was designed, selecting 71 patients suffering facial soft tissue subcutaneous defects fulfilling the inclusion criteria. Two groups were descri-bed according to reconstructive and aesthetic surgery. Facial lipostructure technique was used as the standard surgical procedure and a biopsy of the grafted adipose tissue was taken at 14 months follow-up. The stereological method was used to measure the quantitative volumetric parameters of the fat at the injection time and at the biopsy time. By means of simple mathematical equations, the volumetric and numerical take rate could be obtained. Descriptive and quantitative statistical analyses of all data were performed. Fat auto-grafts on the face survive two thirds of the injec-ted volume at 14 months follow-up. The unique confirmation proof of survival of fat auto-grafts is the histological evidence and demonstration of viable adipose tissue in recipient sites and its quantification by a volumetric, accurate and objective valuation method, as it is provided by Stereology.

Keywords : Fat grafting; Adipose tissue; Fat survival; Stereology.

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