SciELO - Scientific Electronic Library Online

 
vol.43 número3Mano eléctrica quemada: casuística de 5 años en el Hospital Universitario Rio Hortega de Valladolid, España índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google

Compartir


Cirugía Plástica Ibero-Latinoamericana

versión On-line ISSN 1989-2055versión impresa ISSN 0376-7892

Resumen

OJEDA-REGIDOR, Ángela; MARTINEZ-MENDEZ, José-Ramón; GONZALEZ-MIRANDA, Álvaro  y  CASADO-PEREZ, César. Evaluation of surgical times and transfusions in burn patients treated with enzymatic debridement. Cir. plást. iberolatinoam. [online]. 2017, vol.43, n.3, pp.223-230. ISSN 1989-2055.  http://dx.doi.org/10.4321/s0376-78922017000400002.

Background and Objective

During the last years, results have been published demonstrating fast, efficient and specific enzymatic debridement of burned tissues with the use of a concentrate of proteolytic enzymes enriched with bromelain (Nexobrid®, Mediwound, Germany).

In this study we compare the use of Nexobrid® against a Control Group with standard treatment, in order to evaluate; the number of surgical procedures performed, the colonization of the surgical bed, the need for scarotomies, as well as the number of transfusions of the treated patients according to the total burned surface area (TBSA).

Methods

We conduct a retrospective study evaluating 65 patients (mean age 46.87 years) treated with Nexobrid® between September 2015 and December 2016. We compare this population with a control group of 177 patients (mean age 48.24 years) treated with tangential excision from January to December 2014. The Control Group was homogeneous to Nexobridto Nexobrid® Group. Group. Both groups were stratified according to their TBSA in 2 groups: more or less than 15%.

Results

We found lesser number of days from burn and hospital admission to the first debridement for the Nexobrid® Group regardless of the burned body surface. Statistically significant differences were obtained for the number of surgeries (p <0.01) in the subgroup with <15% TBSA. We evaluated the colonization without obtaining statistically significant differences between the groups. The number of scarotomies carried out in the Nexobridto Nexobrid® Group. Group was significantly lower than in the Control Group when comparing the populations with >15% TSBA. The transfusion requirements were lower in the Nexobrid® Group compared to the Control Group in patients with >15% TBSA (p <0.05).

Conclusions

The use of Nexobrid® allows reducing the number of surgeries and the time elapsed to first debridement without increasing the rate of colonization when compared to the Control Group. Early enzymatic debridement reduces the need for scarotomies in >15% TBSA patients. The use of Nexobrid® reduces the need for blood transfusion in patients with >15% TBSA.

Palabras clave : Burns; Debridement; Enzymatic debridement; Bromelain; Transfusion.

        · resumen en Español     · texto en Español     · Español ( pdf )